Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-05-16
2006-05-16
Spivack, Phyllis G. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S183000
Reexamination Certificate
active
07045523
ABSTRACT:
A method of treating BCR-ABL positive leukemia in a warm-blooded animal comprising administering the combination of N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine, or a pharmaceutically acceptable salt thereof, and telomestatin is disclosed. The combination may optionally have a pharmaceutically acceptable carrier, and the compounds may be administered for simultaneous, separate or sequential use.
REFERENCES:
patent: 0 819 433 (1998-01-01), None
patent: 1 123 937 (2001-08-01), None
patent: WO 99/03854 (1999-01-01), None
patent: WO 00/18234 (2000-04-01), None
patent: WO 01/02377 (2001-01-01), None
Tauchi et al., Oncogene, 22, 5338-5437 (2003).
Nakajima et al., “Efficacy of SCH66336, The Farnesyl Transferase Inhibitor, in Conjuction with Other Antileukemic Agents Against Glivec-resistant BCR-ABL-positive Cells”,Blood, vol. 98, No. 11, Pt. 1, p. 575a (2001)—Abstract 2002:209875 BIOSIS.
Shin-ya et al., “Telomestatin, a Novel Telomerase Inhibitor fromStreptomyces anulatus”, J Am Chem Soc, vol. 123, pp. 1262-1263 (2001).
Taudi et al., “Activity of a Novel Telomerase Inhibitor, Telomestatin, Against Glivec-resistant BCR-ABL-positive Cells”,Blood, vol. 98, No. 11, Pt. 1, p. 616a (2001)—Abstract 2002:220199 BIOSIS.
Dohmann George R.
Jackson Oona A.
McNally Lydia T.
Novartis AG
Spivack Phyllis G.
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