Comb for forming sample wells, with enlarged loading areas, in e

Details Comb for forming sample wells, with enlarged loading areas, in e Comb for forming sample wells, with enlarged loading areas, in e

1998-06-16

2000-01-25

Warden, Jill

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

204606, 204616, G01N 2726, G01N 27447

Patent

active

060174366

ABSTRACT:
A gel for electrophoresis in a horizontal mode which contains at least one sample well with an enlarged loading area that is formed in an elevated gel segment. At least a front wall of the sample well consists of a substantially vertical part and a non-vertical part, where the non-vertical part is declined at an angle sufficiently steep that the sample loaded on the non-vertical part slides down into the sample well. Any sample molecules that during electrophoresis enter the gel through the non vertical part of the front wall migrate only through the elevated gel segment. They also exit this segment, so that substantially no double bands, which could complicate the interpretation of experimental results, are detected.

REFERENCES:
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patent: 5318682 (1994-06-01), Singer
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patent: 5514255 (1996-05-01), Gautsch et al.
patent: 5618399 (1997-04-01), Gautsch et al.
patent: 5627022 (1997-05-01), Renfrew et al.

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