Comb elements rotating in position to place selected slit arrays

Details Comb elements rotating in position to place selected slit arrays Comb elements rotating in position to place selected slit arrays

1996-02-02

1997-04-08

Gorgos, Kathryn L.

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

204615, 204465, G01N 2726

Patent

active

056183992

ABSTRACT:
A spacer-comb element including (i) a longitudinal central axis and (ii) three or more, preferably four, teeth arrays radially extending about the central axis and extending along a length thereof, serves to emplace arrayed slit apertures within flat sheets of a gel state material that is itself suitable to receive samples upon which electrophoresis may be performed. The spacer-comb element is placed between the sidewalls of, and engaged by, a tray holding the gel material in a central reservoir so that the teeth of only a selected one array extend downwards into the tray. An opposite, upwards-extending, teeth array engages the underside of an overlying tray, preferably at an optional complimentary groove feature on the tray's underside, so as to support the tray. A stack of trays and intervening spacer-comb elements is used as a system and in a method for preparing multiple trays of a gel state material, normally an agarose gel, all in one step at the same time, each prepared gel having arrayed slit apertures of selected number(s) and at selected location(s).

REFERENCES:
patent: 2507373 (1947-12-01), Finkelstein
patent: 5337765 (1994-08-01), Wong

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