Column holder for on-column photometric detection

Optics: measuring and testing – With plural diverse test or art

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73 611C, 356410, 356244, G01N 3074

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active

048547000

ABSTRACT:
A column holder for on-column photometric detection capillary liquid chromatography incorporating a body and a pair of straight edges attached to the body. The straight edges can be conveniently made from a razor blade. The body has two passageways through it that are transverse and intersecting. The first passageway is dimensioned so that a capillary column can be slipped into it or removed from it by hand. The other passageway is for the passage of a light beam from a liquid chromatography photometric detector. The straight edges are slightly separated to form an optical slit in front of the capillary column and are securely clamped to the body of the column holder. A capillary column can be removed from the column holder and be replaced with another capillary column without damaging it and without the necessity of repositioning the slit.

REFERENCES:
patent: 4008397 (1977-02-01), Zdrodowski
patent: 4375163 (1983-03-01), Yang
patent: 4601582 (1986-07-01), Casey, Jr.
patent: 4605305 (1986-08-01), Lenoir et al.
Larry A. Spino, Soon M. Han, Daniel W., Armstrong, Albert R. Parrott, "Inexpensive, Low-Dead Volume Flow Cells for Microcolumn LC", Journal of Liquid Chromatography, vol. 10 (8 & 9), 1987, pp. 1603-1611.
Robert Tijssen, Jaap Bos, M. Emile von Kreveld, "Hydrodynamic Chromatography of Macromolecules in Open Microcapillary Tubes", Analytical Chemistry, vol. 58, No. 14, Dec. 1986, pp. 3036-3044.

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