Column agglutination assay and device using biphasic centrifugat

Details Column agglutination assay and device using biphasic centrifugat Column agglutination assay and device using biphasic centrifugat

1993-08-26

1996-09-03

Reifsnyder, David A.

Liquid purification or separation

Processes

Separating

210518, 210782, 422 72, 422101, 435 71, 436177, B01D 2126

Patent

active

055520642

ABSTRACT:
The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells.

REFERENCES:
patent: 3586064 (1969-09-01), Brown
patent: 3799342 (1974-03-01), Greenspan
patent: 3932277 (1976-01-01), McDermott et al.
patent: 4035294 (1977-07-01), Landers et al.
patent: 4140662 (1979-02-01), Reckel et al.
patent: 4244694 (1981-01-01), Farina et al.
patent: 4435293 (1984-03-01), Graham, Jr. et al.

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