Color-encoding and in-situ interrogation of matrix-coupled...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S004000, C435S007100, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C436S518000, C436S501000, C530S333000, C530S334000

Reexamination Certificate

active

07083914

ABSTRACT:
A method and apparatus for the physico-chemical encoding of a collection of beaded resin (“beads”) to determine the chemical identity of bead-anchored compounds by in-situ interrogation of individual beads. The present invention provides method and apparatus to implement color-coding strategies in applications and including the ultrahigh-throughput screening of bead-based combinatorial compounds libraries as well as multiplexed diagnostic and environmental testing and other biochemical assays.

REFERENCES:
patent: 3982182 (1976-09-01), Hogg
patent: 4456513 (1984-06-01), Kawai et al.
patent: 4717655 (1988-01-01), Fulwyler
patent: 5194300 (1993-03-01), Cheung
patent: 5244636 (1993-09-01), Walt et al.
patent: 5244813 (1993-09-01), Walt et al.
patent: 5250264 (1993-10-01), Walt et al.
patent: 5252494 (1993-10-01), Walt
patent: 5254477 (1993-10-01), Walt
patent: 5298741 (1994-03-01), Walt et al.
patent: 5306618 (1994-04-01), Prober et al.
patent: 5320814 (1994-06-01), Walt et al.
patent: 5362653 (1994-11-01), Carr et al.
patent: 5405784 (1995-04-01), Van Hoegaerden
patent: 5480723 (1996-01-01), Klainer et al.
patent: 5496997 (1996-03-01), Pope
patent: 5512490 (1996-04-01), Walt et al.
patent: 5565324 (1996-10-01), Still et al.
patent: 5567627 (1996-10-01), Lehnen
patent: 5573909 (1996-11-01), Singer et al.
patent: 5585069 (1996-12-01), Zanzucchi et al.
patent: 5593838 (1997-01-01), Zanzucchi et al.
patent: 5633724 (1997-05-01), King et al.
patent: 5633972 (1997-05-01), Walt et al.
patent: 5650489 (1997-07-01), Lam et al.
patent: 5652059 (1997-07-01), Margel
patent: 5674698 (1997-10-01), Zarling et al.
patent: 5690894 (1997-11-01), Pinkel et al.
patent: 5700897 (1997-12-01), Klainer et al.
patent: 5723218 (1998-03-01), Haugland et al.
patent: 5728529 (1998-03-01), Metzker et al.
patent: 5744305 (1998-04-01), Fodor et al.
patent: 5779976 (1998-07-01), Leland et al.
patent: 5807755 (1998-09-01), Ekins
patent: 5814524 (1998-09-01), Walt et al.
patent: 5837551 (1998-11-01), Ekins
patent: 5874219 (1999-02-01), Rava et al.
patent: 5939021 (1999-08-01), Hansen et al.
patent: 5961923 (1999-10-01), Nova et al.
patent: 5965452 (1999-10-01), Kovacs
patent: 5968736 (1999-10-01), Still et al.
patent: 5989835 (1999-11-01), Dunlay et al.
patent: 6023540 (2000-02-01), Walt et al.
patent: 6048690 (2000-04-01), Heller et al.
patent: 6083763 (2000-07-01), Balch
patent: 6090545 (2000-07-01), Wohlstadter et al.
patent: 6090912 (2000-07-01), Lebl et al.
patent: 6200737 (2001-03-01), Walt et al.
patent: 6251691 (2001-06-01), Seul
patent: 6266459 (2001-07-01), Walt et al.
patent: 9306121 (1993-04-01), None
patent: WO 93/06121 (1993-04-01), None
patent: 9324517 (1993-12-01), None
patent: 9512808 (1995-05-01), None
patent: 9607917 (1996-03-01), None
patent: 9714028 (1997-04-01), None
patent: 9740383 (1997-10-01), None
patent: 9806007 (1998-02-01), None
patent: 9853300 (1998-11-01), None
patent: 9918434 (1999-04-01), None
patent: 9919515 (1999-04-01), None
Boyce et al (J. Am. Chem. Soc., vol. 116, No. 17, 1994).
Barnard, et al., “A fibre-optic chemical sensor with discrete sensing sites,” Nature, vol. 353: 338-340 (1991).
Campian, et al. “Colored and Fluorescent Solid Supports,” Innovation and Perspectives in Solid-Phase Synthesis . Ed: E. Birmingham (Mayflower, London), pp. 469-472 (1994).
Pope, “Fiber optic chemical microsensors employing optically active silica microspheres,” SPIE, vol. 2388 : 245-256 (1995).
Grazia et al., “In-vivo biomedical monitoring by Fiber-Optic System,” Journal of Lightwave Technology, 13, 1396-1406 (1995).
Bangs, “Immunological Applications of Microspheres,” The Latex Course, Bangs Laboratories (Apr. 1996).
“Fluorescent Microspheres (Tech. Note #19),” Bangs Laboratories (1997).
Egner, et al., “Tagging in combinatorial chemistry: the use of coloured and fluorescent beads,” Chem. Commun. pp. 735-736 (1997).
Fulton, et al., “Advanced multiplexed analysis with the FlowMetrix system,” Clinical Chemistry, vol. 43:9 , pp. 1749-1756 (1997).
Scott et al., “Properties of fluorophores on solid resins; implications for screening, encoding and reaction monitoring,” Bioorganic & Medicinal Chemistry Letters, 7:12, pp. 1567-1572 (1997).
Healey et al., “Fiberoptic DNA sensor array capable of detecting point mutations,” Analytical Biochemistry, vol. 251, pp. 270-279 (1997).
“Microsphere Selection Guide,” Bangs Laboratories, Inc. (Fisher, IN) (Sep. 1998).
Micheletto et al.,Iangmuir,vol. 11, 3333-3336 (1995).
Nagayama et al.,Phase Transitions,vol. 45, 185-203 (1993).
Houghten. General Method for the rapid solid-pahse synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc. Natl. Acad. Sci. USA. vol. 82: 5131-5135 (1985).
Roberts et al. “Patterned Magnetic bar array for high-throughput DNA detection”. IEEE transactions on magnetics. vol. 40, No. 4: 3006-3008 (2004).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Color-encoding and in-situ interrogation of matrix-coupled... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Color-encoding and in-situ interrogation of matrix-coupled..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Color-encoding and in-situ interrogation of matrix-coupled... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3632717

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.