Colonic drug delivery system

Details Colonic drug delivery system Colonic drug delivery system

1994-06-24

1996-07-16

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424480, 424482, 424493, 424494, 424495, 424497, A61K 932, A61K 936, A61K 958, A61K 962

Patent

active

055365078

ABSTRACT:
A three component pharmaceutical formulation of one or more pharmacologically active substances such that greater than 80% of the pharmacologically active substance will be released in the large intestine. The first component comprises the pharmacologically active substance, microcrystalline cellulose, a pH-sensitive polymer, and optionally an osmotic agent. The second component is a delayed release coating, and the third component is an enteric coating.

REFERENCES:
patent: 4309404 (1982-01-01), DeNeale et al.
patent: 4432966 (1984-02-01), Zeitoun et al.
patent: 4837030 (1989-06-01), Valarose, Jr. et al.
patent: 4882169 (1989-11-01), Ventouras
patent: 4910021 (1990-03-01), Davis et al.
patent: 5283065 (1994-02-01), Doyon et al.
patent: 5326570 (1994-07-01), Rudnic et al.
S.S. Davis, "The Design and Evaluation of Controlled Release Systems for the Gastrointestinal Tract", J. of Controlled Release, 2, (1985) 27-38.
Remington's Pharmaceutical Sciences, 1990, 18th. Edition, Philadelphia College of Pharmacy and Science, Chapter 66, Pharmaceutical Necessities, pp. 1305, 1313, & 1327.

Affiliated with

Also associated with

Rating

Colonic drug delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Colonic drug delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Colonic drug delivery system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1782886