Colonic delivery of nicotine to treat inflammatory bowel disease

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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424469, 424474, 424482, 424486, A61K 902, A61K 932, A61K 31465, A61K 3178

Patent

active

058890289

ABSTRACT:
A method is provided to treat inflammatory bowel disease by locally administering to the colon an effective amount of nicotine or a pharmaceutically acceptable salt thereof, preferably via formulations adapted for delayed oral release or rectal administration. Further provided is a novel formulation for the oral administration of nicotine comprising a polyacrylic polymer complexed with nicotine.

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