Colon disease targets and uses thereof

Details Colon disease targets and uses thereof Colon disease targets and uses thereof

2008-02-19

2010-11-30

Aeder, Sean E (Department: 1642)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

Reexamination Certificate

active

07842466

ABSTRACT:
The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.

REFERENCES:
patent: 6107048 (2000-08-01), Goldenring et al.
Tockman et al (Cancer Res., 1992, 52:2711s-2718s).
Stein et al (Cancer Research, Apr. 2004, 64:2805-2816).
Charalambous et al (Br J Cancer, May 2003, 88(10): 1598-1604).

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