Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2005-06-15
2010-06-29
Tsang, Cecilia (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S255010, C506S015000
Reexamination Certificate
active
07745413
ABSTRACT:
The use of a collection of compounds of general formula (I), wherein: n is 0 or 1; p represents an integer between 1 and 6; r represents an integer between 1 and 12; R1and R′1represent in particular a hydrogen atom; R2represents an amino acid side chain or an amino acid derivative; R3represents a group derived from a carboxylic acid, bearing a basic entity; R4represents in particular an alkyl group containing 1 to 10 carbon atoms; and A represents a hydrogen atom, a protecting group or a tracing group, in particular a fluorophor, a coloring agent or a quencher, for determining, through binding studies, ligands of receptors whose ligand is unknown or whose ligand useful for carrying out specific affinity binding assays is unknown.
REFERENCES:
patent: 2007/0249013 (2007-10-01), Hibert et al.
patent: 2008/0176763 (2008-07-01), Hibert et al.
patent: 2841246 (2003-12-01), None
patent: WO9949067 (1999-09-01), None
patent: 02/072613 (2002-09-01), None
Ciolina et al. Coupling of Nuclear Localization Signals to Plasmid DNA and Specific Interaction of the Conjugates with Importin alpha. Bioconjugate Chem 1999. vol. 10, pp. 49-55.
Franchet Christel Anne
Galzi Jean-Luc
Guillier Fabrice Yves
Hibert Marcel Francois Louis
Pattus Franc Emile Jean
Centre National de la Recherche Scientifique "CNRS"
Cordero Garcia Marcela M
Tsang Cecilia
Universite Louis Pasteur
Young & Thompson
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