Collapsin response mediator protein-1

Details Collapsin response mediator protein-1 Collapsin response mediator protein-1

2008-04-08

2008-04-08

Rawlings, Stephen L. (Department: 1643)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C530S350000, C436S064000, C536S023500

Reexamination Certificate

active

10180198

ABSTRACT:
This invention is based on the discovery of an association of Collapsin Response Mediator Protein-1 (CRMP-1) with tumor metastasis. The level of CRMP-1 protein or mRNA can be used as an indicator of cellular invasiveness and of a test compound's ability to alter cellular invasiveness. The level of CRMP-1 protein can also be altered, e.g., to reduce invasiveness.

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