Collagen XXII, a novel human collagen and uses thereof

Details Collagen XXII, a novel human collagen and uses thereof Collagen XXII, a novel human collagen and uses thereof

2006-10-20

2008-11-18

Martinell, James (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C530S324000, C530S326000, C530S328000, C530S356000, C530S387100

Reexamination Certificate

active

07452684

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated collagen XXII nucleic acid molecules, which encode a novel collagen. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing collagen XXII nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a collagen XXII gene has been introduced or disrupted. The invention still further provides isolated collagen XXII proteins, fusion proteins, antigenic-peptides and anti-collagen XXII antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

REFERENCES:
patent: 2003/0190715 (2003-10-01), Grosse et al.
patent: 2004/0009474 (2004-01-01), Leach et al.
patent: WO 01/92523 (2001-12-01), None
Lee et al., “Biomedical applications of collagen,” Int. J. Pharm., 221:1-22 (2001).
Myllyharju et al., “Collagens and collagen-related diseases,” Ann. Med., 33:7-21 (2001).
Database EST Accession No. BF196343, NCI-CGAP “7n68f06.x1 NCI—CGAP—Ov18Homo sapienscDNA clone,” Nov. 2000, 4 pages.

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