Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-10-20
2008-11-18
Martinell, James (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S324000, C530S326000, C530S328000, C530S356000, C530S387100
Reexamination Certificate
active
07452684
ABSTRACT:
The invention provides isolated nucleic acids molecules, designated collagen XXII nucleic acid molecules, which encode a novel collagen. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing collagen XXII nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a collagen XXII gene has been introduced or disrupted. The invention still further provides isolated collagen XXII proteins, fusion proteins, antigenic-peptides and anti-collagen XXII antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
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patent: 2004/0009474 (2004-01-01), Leach et al.
patent: WO 01/92523 (2001-12-01), None
Lee et al., “Biomedical applications of collagen,” Int. J. Pharm., 221:1-22 (2001).
Myllyharju et al., “Collagens and collagen-related diseases,” Ann. Med., 33:7-21 (2001).
Database EST Accession No. BF196343, NCI-CGAP “7n68f06.x1 NCI—CGAP—Ov18Homo sapienscDNA clone,” Nov. 2000, 4 pages.
Bruckner-Tuderman Leena
Brunken William Joseph
Burgeson Robert Eugene
Keene Douglas R.
Koch Manuel
Fish & Richardson P.C.
Martinell James
The General Hospital Corporation
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