Collagen XXII, a novel human collagen and uses thereof

Details Collagen XXII, a novel human collagen and uses thereof Collagen XXII, a novel human collagen and uses thereof

2006-10-24

2006-10-24

Martinell, James (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S320100, C435S252300, C435S325000, C536S023500, C536S023100

Reexamination Certificate

active

07125666

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated collagen XXII nucleic acid molecules, which encode a novel collagen. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing collagen XXII nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a collagen XXII gene has been introduced or disrupted. The invention still further provides isolated collagen XXII proteins, fusion proteins, antigenic peptides and anti-collagen XXII antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

REFERENCES:
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patent: WO 01/92523 (2001-12-01), None
Lee et al. “Biomedical applications of collagen”, 2001,Int J Pharm, vol. 221(1-2):1-22.
Myllyharju et al., “Collagens and collagen-related diseases”, 2001, Ann Med., vol. 33(1):7-21.
Database EST Accession No. BF196343, NCI-CGAP “7n68f06.x1 NCI—CGAP—Ov18 Homo sapiens cDNA clone,” Nov. 2000, 4 pages.
Form PCT/ISA/220; “Notification of the International Search Report or the Declaration,” as issued on Apr. 8, 2004, by the International Searching Authority, 6 pages.

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