Collagen wound healing matrices and process for their production

Details Collagen wound healing matrices and process for their production Collagen wound healing matrices and process for their production

1988-12-16

1990-08-21

Page, Thurman

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424423, 424424, 424425, 424426, 424444, A61K 900

Patent

active

049504835

ABSTRACT:
Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves an an effective sustained delivery system for synergistic combinations of FGF and TGF-B.

REFERENCES:
patent: 3742955 (1973-07-01), Battista et al.
patent: 3810473 (1974-05-01), Cruz, Jr. et al.
patent: 4238480 (1980-12-01), Sawyer
patent: 4279812 (1981-07-01), Cioca
patent: 4320201 (1982-03-01), Berg et al.
patent: 4390519 (1983-06-01), Sawyer
patent: 4404970 (1983-09-01), Sawyer
patent: 4412947 (1983-11-01), Cioca
patent: 4415628 (1983-11-01), Cioca et al.
patent: 4515637 (1985-05-01), Cioca
patent: 4544516 (1985-10-01), Hughes et al.
patent: 4553974 (1985-11-01), Dewanjee
patent: 4557764 (1985-12-01), Chu
patent: 4578067 (1986-03-01), Cruz, Jr.
patent: 4725671 (1988-02-01), Chu et al.
patent: 4789663 (1988-12-01), Wallace et al.
patent: 4795467 (1989-01-01), Piez et al.
C. J. Doillon et al., J Biomed Mat Res (1986) 20: 1219-28.

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