Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-08-11
2010-10-26
Yu, Misook (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100
Reexamination Certificate
active
07820401
ABSTRACT:
Methods of determining whether a cancer is progressing by measuring surface-bound collagen VIα3 are provided. Also provided are methods of identifying hyperplasia in a tissue by measuring surface-bound collagen VIα3. Additionally, methods of identifying carcinoma in a tissue by measuring surface-bound collagen VIα3 are provided. Further provided are methods of imaging carcinoma in a tissue by staining the tissue with a specific binding partner to collagen VIα3. Methods of treating a cancer by preventing binding of collagen VIα3 onto cells of the cancer are additionally provided.
REFERENCES:
patent: 2002/0072503 (2002-06-01), Xu et al.
patent: 2004/0029114 (2004-02-01), Mack et al.
Sherman-Baust et al, Cancer Cell, Apr. 2003, 3:377-386.
Iyengar Puneeth
Scherer Philipp E.
Albert Einstein College of Medicine of Yeshiva University
Amster Rothstein & Ebenstein LLP
Halvorson Mark
Yu Misook
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