Collagen type III synthetic peptides for collagen resorption...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues

Reexamination Certificate

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C530S327000, C530S328000, C530S329000, C530S330000, C514S017400

Reexamination Certificate

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06916903

ABSTRACT:
Peptides synthesized to match C-telopeptide components of type III collagen degradation products in body fluids, selected from among EKAGGF (SEQ ID NO:39), IGGEKAGG (SEQ ID NO:40), IGGEKAGGF (SEQ ID NO:41), IAGIGGEKAGG (SEQ ID NO:42), IAGIGGEKAGGF (SEQ ID NO:43), and EKAGG (SEQ ID NO:44) are useful as immunogens and antigens in collagen resorption assays.

REFERENCES:
patent: 4312853 (1982-01-01), Timpl
patent: 4504587 (1985-03-01), Timpl et al.
patent: 4628027 (1986-12-01), Gay
patent: 4973666 (1990-11-01), Eyre
patent: 5140103 (1992-08-01), Eyre
patent: 5300434 (1994-04-01), Eyre
patent: 5316914 (1994-05-01), Oshima et al.
patent: 5320970 (1994-06-01), Eyre
patent: 5342756 (1994-08-01), Risteli et al.
patent: 5702909 (1997-12-01), Eyre
patent: 5817755 (1998-10-01), Eyre et al.
patent: 1287801 (1991-08-01), None
patent: 0 089 008 (1983-09-01), None
patent: 0 289 930 (1988-11-01), None
patent: 0 298 210 (1989-01-01), None
patent: 0 304 292 (1989-02-01), None
patent: 0 339 443 (1989-11-01), None
patent: 0 505 210 (1992-09-01), None
patent: 0 699 752 (1996-03-01), None
patent: 0 718 309 (1996-06-01), None
patent: 2 205 643 (1988-12-01), None
patent: WO 88/08980 (1988-11-01), None
patent: WO 89/04491 (1989-05-01), None
patent: WO 89/12824 (1989-12-01), None
patent: WO 91/08478 (1991-06-01), None
patent: WO 91/08478 (1991-06-01), None
patent: WO 92/21698 (1992-12-01), None
patent: WO 94/03813 (1994-02-01), None
patent: WO 94/14070 (1994-06-01), None
patent: WO 94/14844 (1994-07-01), None
patent: WO 94/18563 (1994-08-01), None
patent: WO 95/04282 (1995-02-01), None
patent: WO 95/08115 (1995-03-01), None
patent: WO 96/12193 (1996-04-01), None
patent: WO 96/36645 (1996-11-01), None
Ala-Kokko, L., et al., “Structure of cDNA Clones Coding for the Entire Preproα1(III) Chain of Human Type III Precollagen,”Biochem. J.260:509-516, 1989.
Seibel, M.J., “Komponenten der extrazellulären Gewebematrix als potentielle-Marker” des Bindegewebs-, Knorpel- und Knochenmetabolismus bei Erkrankungen des Bewegungsapparates,Z. Rheumatol.48:6-18, 1989.
Niemelä, O., “Radioimmunoassays for Type III Procollagen Amino-Terminal Peptides in Humans,”Clin. Chem.31(8):1301-1304, 1985.
Loid, H.R., et al., “Molecular Cloning and Carboxyl-Propeptide Analysis of Human Type III Procollagen,”Nucleic Acids Research12(24):9383-9394, 1984.
Pierard, D., et al., “Radioimmunoassay for the Amino-Terminal Sequences of Type III Procollagen in Human Body Fluids Measuring Fragmented Precursor Sequences,”Analytical Biochem.141:127-136, 1984.
Rohde, H., et al., “Radioimmunoassay for Type III Procollagen Peptide and Its Application to Human Liver Disease,”Euro. J. Clin. Invest.9:451-459, 1979.
Eyre, D.R., “Cross-Linking in Collagen and Elastin,”Ann. Rev. Biochem.53:717-748, 1984.
Hasselbalch, H., et al., “Procollagen Type III Aminoterminal Peptide in Serum in Idiopathic Myelofibrosis and Allied Conditions: Relation to Disease Activity and Effect of Chemotherapy,”Am. J. Hematol.33:18-26, 1990.
Hanson, D.A., et al., “A Specific Immunoassay for Monitoring Human Bone Resorption: Quantitation of Type I Collagen Cross-Linked N-Telopeptides in Urine,”J. Bone and Min. Res.7(11):1251-1258, 1992.
Lane, J.M., et al., “Immunofluorescent Localization of Structural Collagen Types in Endochondral Fracture Healing,”Orthopaedic Transactions VI(2):236, 1982.
Kühn, K., “The Classical Collagens: Types I, II, and III,” inStructure and Function of Collagen Types, Academic Press, Inc., 1987, pp. 1-42.
Stoltenberg, M., et al., “Intra-Articular and Circulating Levels of Type and I and III Collagen Markers in Inflammatory and Degenerative Joint Disease,”Acta. Orthop. Scand.66(Suppl 266):147-148, 1995.
Eyre, D.R., et al., “Cross-Linked Telopeptides From Collagen Types I, II and III in Human Urine,” ASBMR Meeting, Sep. 1996.
Horslev-Petersen, K., “Circulating Extracellular Matrix Components as Markers for Connective Tissue Response to Inflammation,”Danish Med. Bul.37(4):308-329, 1990.
Hanson, D.A., and D.R. Eyre, “Molecular Site Specificity of Pyridinoline and Pyrrole Cross-Links in Type I Collagen of Human Bone,”J. Biol. Chem.271(43):26508-26516, 1996.
Myllylä, R., et al., “Markers of Collagen Metabolism in Sera of Patients With Various Rheumatic Disease,”Clinica Chimica Acta183:243-252, 1989.
Macarak, E.J., et al., “Production and Characterization of a Monoclonal Antibody to Human Type III Collagen,”J. Histochem. Cytochem.34(8):1003-1011, 1986, inChem. Abstracts105:95762y, 1986.
Macarak, E.J., et al., “Production and Characterization of a Monoclonal Antibody to Human Type III Collagen,”J. Histochem. and Cytochem.34(8):1003-1011, 1986.
Otter, A., et al., “Conformational Analysis of the Type II and III Collagen α-1 Chain N-Telopeptides by Proton-NMR Spectroscopy and Restrained Molecular Mechanics Calculations,”Biopolymers33(9):1443-1459, 1993, inChem. Abstracts119:264860a, 1993.
Gosslau, B., and H.-J. Barrach, “Enzyme-Linked Immunosorbent Microassay for Quantification of Specific Antibodies to Collagen Type I, II, III,”J. Immunol. Meth.29:71-77, 1979.
Atley, L., et al., “A Selective Inhibitor of Collangenase-3 Blocks the Release of Hydroxyproline and a Metalloproteinase Specific Neoepitope, Coll II CTx, From Bovine Cartilege Exposed to IL-1α,”Arth. Rheum.40(9S):584, 1997.
Niemelä, O., et al., “Heterogeneity of the Antigens Related to the Aminoterminal Propeptide of Type III Procollagen in Human Serum,”Clinica Chimica Acta124:39-44, 1982.
Atley, L.M., et al., “Matrix Metalloproteinase-Mediated Release of Immunoreactive Telopeptides From Cartilage Type II Collagen,”44th Annual Meeting, Orthop. Res. Soc., New Orleans, Mar. 16-19, 1998.
Moskowitz, R.W., et al., “Type II Collagen C-Telopeptide 2B4 Epitope Is a Marker for Cartilage Degradation in Familial Osteoarthritis,”Meeting of Amer. Coll. Rheum., San Diego, Nov. 8-12, 1998.
Eyre, D.R., et al., “Biochemical Markers of Bone and Cartilage Collagen Degradation,”Combined Orthopaedic Research Societies Meeting, Vittel, France, Sep. 28-30, 1998.
Sheridan, C., “Osteometer Targets Collagen for Osteoporosis, Arthritis Tests,”BioWorld International, Dec. 3, 1997, p. 3.
Atley, L.M., et al., “Collagen Type II Cross-Linked Telopeptides, a Promising Marker for Cartilage Degradation in Arthritis,”Combined Orthopaedic Research Societies Meeting, Hamamatsu, Japan, 1998.
Otter, A., et al., “Conformational Analysis of the Type II and Type III Colagen α-1 Chain N-Telopeptides by H-NMR Stpectroscopy and Restrained Molecular Mechanics Calculations,”Biopolymers33:1443-1459, 1993.

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