Collagen modulators for use in photoablation excimer laser kerat

Details Collagen modulators for use in photoablation excimer laser kerat Collagen modulators for use in photoablation excimer laser kerat

1992-09-09

1996-02-20

Sykes, Angela D.

Surgery

Miscellaneous

Methods

522 68, A61B 1700

Patent

active

054921350

ABSTRACT:
A method of smoothing irregular corneal surfaces and removing protuberances from corneal surfaces by photoablative excimer laser keratectomy is provided. Collagen compositions for use in making collagen modulators useful in photoablative procedures are described. These compositions are applied to irregular corneal surfaces in sufficient amounts to at least fill in depressions or other irregularities on a corneal surface and are converted into a modulator, as a gel or polymerized film, prior to photoablation. The collagen modulators facilitate the photoablative smoothing of irregular corneal surfaces and protect adjacent corneal tissue from undesired photoablation.

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