Coliform bacillus having a gene for the production of staphyloki

Details Coliform bacillus having a gene for the production of staphyloki Coliform bacillus having a gene for the production of staphyloki

1982-10-15

1985-07-30

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

435 68, 435 70, 435 71, 435212, 435219, 435220, 435253, 435317, 536 27, 935 14, 935 29, 935 73, 935 82, C12P 2100, C12P 2102, C12P 2104, C12N 948, C12N 950, C12N 120, C12N 100, C12N 1500, C07H 2104

Patent

active

045322112

ABSTRACT:
Novel coliform bacillus useful for industrial production of staphylokinase, a fibrinolytic enzyme, and process for the production of staphylokinase using said microbe are provided. The novel microbe comprises a recombinant DNA, carrying genetic information for the production of staphylokinase, said genetic information being DNA derived from a temperate phage DNA of Staphylococcus aureus.

REFERENCES:
patent: 4366246 (1982-12-01), Riggs
Blair et al., "Phage Typing of Staphylococci", pp. 771-784, (1961), Bull. World Health Org.
Mason et al., "Can. J. Microbiol." vol. 21, pp. 1113-1116, (1975).
Kondo et al., "Infection and Immunity", vol. 18, No. 2, pp. 266-272, (1977).
Kondo et al., "Staphylococcal Phages Mediating the Lysogenic Conversion of Staphylokinase", pp. 357-362, (1981).
Cohen et al., "Proc. Nat. Acad. Sci", vol. 70, No. 11, pp. 3240-3244, (1973).
Chang et al., "Proc. Nat. Acad. Sci.", vol. 71, No. 4, pp. 1030-1034, (1974).
Bolivar et al., "Construction and Characterization of New Cloning Vehicles", pp. 95-113, (1977).
Talmadge et al., "Proc. Natl. Acad. Sci.", vol. 77, No. 6, pp. 3369-3373, (1980).
Lofdahl et al: J. Virol. 37, 795, (1981).
Sako et al: Mol Gen. Genet. 190, 271, (1983).
Kondo et al: In: Jeljaszewicz (ed), Staphylococci and Staphylococcal Infections, Gustav Fisher Verlag, New York, p. 357, (1981).

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