Coherent anti-Stokes Raman device

Details Coherent anti-Stokes Raman device Coherent anti-Stokes Raman device

1981-02-04

1983-09-20

Evans, F. L.

Optics: measuring and testing

By dispersed light spectroscopy

With raman type light scattering

G01J 344

Patent

active

044052375

ABSTRACT:
A coherent anti-Stokes Raman spectroscopic (CARS) imaging device especially adapted to observe specific molecular groups in living cells. Two laser beam pulses of different wavelengths in the visible or UV spectra and of picosecond duration are used to simultaneously illuminate a sample (e.g., a living cell) containing molecules of the type it is desired to observe. By proper selection of the laser frequencies, the molecules are excited to emit characteristic coherent anti-Stokes radiation which can be imaged through a microscope or other device.

REFERENCES:
patent: 4195930 (1980-04-01), Delhaye et al.
"Coherent Anti-Stokes Raman Spectroscopy", Klauminzer et al., Opto-Electrcs, Jun. 1977, pp. 183-190.
"Puscars: A Method for Suppression of Nonresonant Background", Kamza et al., Optics Letters, vol. 5, #3, 1980.
A Review of the Theory & Application of CARS, Tolles et al, Applied Spectroscopy, vol. 31, No. 4, 1977, pp. 253-271.
Gas Concentration Measurement by Coherent Raman Anti-Stokes Scattering, Regneir et al, paper given at AIAA 6th Fluid & Plasma Dynamics Conference, Palm Springs, CA, Jul. 16-18, 1973, (Paper No. 73-702).

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