Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Hormone or other secreted growth regulatory factor,...
Reexamination Certificate
2011-01-11
2011-01-11
Shafer, Shulamith H. (Department: 1647)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Hormone or other secreted growth regulatory factor,...
C424S185100, C514S012200
Reexamination Certificate
active
07867500
ABSTRACT:
The invention provides a new glucocorticoid receptor coactivator named STAMP (Steroid receptor coactivator-1 and Transcription intermediary factor-2 Associated Modulatory Protein) that can modulate transcription of glucocorticoid-, progesterone-, mineralocorticoid- and androgen-responsive genes. The invention also provides antibodies that can bind STAMP and modulate its activity. In addition, the invention provides antisense, ribozyme and siRNA STAMP nucleic acids that can modulate the expression of STAMP. Also provided are compositions and methods for modulating glucocorticoid-responsive gene expression and for treating a variety of diseases and conditions.
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He Yuanzheng
Simons, Jr. S. Stoney
Shafer Shulamith H.
Swanson & Bratschun L.L.C.
The United States of America as represented by the Department of
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