Coenzyme A disulfide reductase, and inhibitors thereof useful as

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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435 243, 4353201, 4352523, 435 6, 536 232, C12N 902, C12N 1500, C12Q 137, C07H 2104

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active

061070688

ABSTRACT:
An isolated and purified Coenzyme A disulfide reductase (CoADR) is provided. Oligonucleotides encoding the CoADR, vectors and host cells containing such oligonucleotides are also provided. In addition, antibodies reactive with the CoADR are provided, as are methods of isolating the CoADR, producing recombinant CoADR, using CoADR for screening compounds for CoADR-modulating activity, and detecting organisms which produce CoADR a test sample. Methods for identifying a gene encoding a CoADR are also provided.

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