Chemistry: molecular biology and microbiology – Vector – per se
Patent
1995-06-06
1998-06-02
Degen, Nancy
Chemistry: molecular biology and microbiology
Vector, per se
435 691, 435 701, 435 711, 43525233, 530350, 536 231, 536 241, C12N 1570, C12N 1579, C12P 2102, C07K 1447
Patent
active
057598533
ABSTRACT:
A plasmid containing a recombinant DNA molecule coding for a protein having the activity of an interferon regulatory factor-1 (IRF-1) and promoter and regulator sequences thereof, are described.
REFERENCES:
patent: 5616699 (1997-04-01), Taniguchi et al.
Taniguchi et al. "Regulatory Cis-Elements & Trans-Actiiy Factors In Cytokine Gene Expression" J Interferon Res 8(Suppl 1) 51 1988.
Fujita etal "Structure Function & Regulation of A Gene Encoding Transcription Factor, IRF, That Mediates IFN-.beta. Gene Expression" J Interferon Res 8(Suppl 1) 53 1988.
Keller etal. "Identification Jan Luducible Factor that Binde TOA Positive Regulatory Element of The Human .beta.-Interferon Gene" PNAS 85 3309-3313 1988.
Miyamoto etal. "Regulated Expression of a Gene Encoding a Nuclear Fautoc, IRF-1, That Specifically Binds to IFN-.beta. Gene Regulatory Elements" Cell 54 903-913 1988.
Au, W.-C. et al., "Distinct activation of murine interferon-.alpha. promoter region by IRF-1/ISFG-2 and virus infection," Nuc. Acids Res. 20(11):2877-2884 (Jun. 1992).
Clark, S.C. and R. Kamen, "The Human Hematopoietic Colony-Stimulating Factors," Science 236:1229-1237 (Jun. 1987).
Dinter, H. and H. Hauser, "Cooperative interaction of multiple DNA elements in the human interferon-.beta. promoter," Eur. J. Biochem. 166(1):103-109 (Jul. 1987).
Fujita, T. et al., "Delimitation and Properties of DNA Sequences Required for the Regulated Expression of Human Interferon-.beta. Gene," Cell 41:489-496 (1985).
Fujita, T. et al., "Interferon-.beta. Gene Regulation: Tandemly Repeated Sequences of a Synthetic 6 bp Oligomer Function As a Virus-Inducible Enhancer," Cell 49(3):357-367 (May 1987).
Fujita, T. et al., "Evidence for nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-.beta. gene regulatory elements," EMBO J. 7(11):3397-3405 (Nov. 1988).
Fujita, T. et al., "Induction of endogenous IFN-.alpha. and IFN-.beta. genes by a regulatory transcription factor, IRF-1," Nature 337:270-272 (Jan. 1989).
Harada, H. et al., "Structurally Similar but Functionally Distinct Factors, IRF-1 and IRF-2, Bind to the Same Regulatory Elements of IFN and IFN-Inducible Genes," Cell 58:729-739 (Aug. 1989).
Harada, H. et al., "Absence of the Type I FN System in EC Cells: Transcriptional Activator (IRF-1) and Repressor (IRF-2) Genes Are Developmentally Regulated," Cell 63(2):303-312 (Oct. 1990).
Keller, A.D. and T. Maniatis, "Identification of an inducible factor that binds to a positive regulatory element of the human .beta.-interferon gene," Proc. Natl. Acad. Sci. USA 85:3309-3313 (May 1988).
Klemm, U. et al., "Rat sperm acrosin: cDNA sequence, derived primary structure and phylogenetic origin," Biochem. Biophy. Acta 1090(2):270-272 (Oct. 1991).
Levy, D. et al., "Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control," Genes & Dev. 2:383-393 (Apr. 1988).
Maniatis, T. et al., "Regulation of Inducible and Tissue-Specific Gene Expression," Science 236:1237-1245 (Jun. 1987).
Miyamoto, M. et al., "Regulated Expression of a Gene Encoding a Nuclear Factor, IRF-1, That Specifically Binds to IFN-.beta. Gene Regulatory Elements," Cell 54:903-913 (Sep. 1988).
Naf, D. et al., "Multimerization of AAGTGA and GAAAGT generates sequences that mediate virus inducibility by mimicking an interferon promoter element," Proc. Natl. Acad. Sci. USA 88(4):1369-1373 (Feb. 1991).
Reis, L.F.I. et al., "Critical role of a common transcription factor, IRF-1, in the regulation of IFN-.beta. and IFN-inducible genes," EMBO J. 11(1):185-193 (Jan. 1992).
Stark, G.R. and I.M. Kerr, "Interferon-Dependent Signaling Pathways: DNA Elements, Transcription Factors, Mutations, and Effects of Viral Proteins," J. Interfer. Res. 12:147-151 (Jun. 1992).
Taniguchi, T. et al., "Regulation of Cytokine Gene Expression," Ann. Rev. Immunol. 6:439-464 (Apr. 1988).
Watanabe, N. et al., "Activation of IFN-.beta. element by IRF-1 requires a post-translational event in addition to IRF-1 synthesis," Nuc. Acids Res. 19(16):4421-4428 (Aug. 1991).
Yamada, G. et al., "Specific depletion of the B-cell population induced by aberrant expression of human interferon regulatory factor 1 gene in transgenic mice," Proc. Natl. Acad. Sci. USA 88(2):532-536 (Jan. 1991).
Fujita Takashi
Taniguchi Tadatsugu
Degen Nancy
Fujita Takashi
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