Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1990-08-09
1992-07-07
Maples, John S.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
546132, A61K 4902, C07D45102
Patent
active
051281180
ABSTRACT:
3.beta.-[4-iodophenyl]-tropan-2.beta.-carboxylic acid methyl ester tartrate is a high affinity binding ligand for neurotransmitters in mammalian brains. It and its congeners may be employed for imaging and other brain scanning techniques that allow the determination of the presence of cocaine receptors, such as neurotransmitters and the like.
REFERENCES:
Madras, B. K. et al, Mol. Pharmacol, "Cocaine Receptors . . . Tropane", 36(4), 1989, pp. 518-524, [CA 112(1):539p].
Abraham Philip
Boja John W.
Carroll Frank I.
Kuhar Michael J.
Lewin Anita H.
Maples John S.
Research Triangle Institute
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