Cocaine receptor binding ligands

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546125, 546132, C07D45102

Patent

active

053808487

ABSTRACT:
Novel compounds show high affinity for specific cocaine receptors in the brain, particularly dopamine transporter sites, and have the formula ##STR1## Wherein Y=CH.sub.2 R.sub.3, CO.sub.2 R.sub.2 or ##STR2## R.sub.1 =hydrogen, C.sub.1-5 alkyl, R.sub.2 =hydrogen, C.sub.1-6 alkyl, C.sub.3-8 cycloalkyl, C.sub.1-4 alkoxy, C.sub.1-6 alkynyl, halogen or amine,

REFERENCES:
patent: 3813404 (1974-05-01), Clarke et al.
patent: 4179567 (1979-12-01), Clarke et al.
patent: 5128118 (1992-07-01), Carroll et al.

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