Cobalt complexes as anticancer agents

Details Cobalt complexes as anticancer agents Cobalt complexes as anticancer agents

1994-06-22

1996-09-10

Nazario-Gonzales, Porfirio

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

556138, A61K 31295, C07F 1506

Patent

active

055546480

ABSTRACT:
New cobalt complexes of nitrogen mustard alkylating agents which have been found to have hypoxia-selective antitumor properties and are thereby useful antitumor agents are described.

REFERENCES:
patent: 2645653 (1953-07-01), Zerweck et al.
patent: 4189306 (1980-02-01), Sandy
J. A. Broanhead, "The Reactivity of Hydroxy Groups in Metal Complexes", J. Am. Chem. Soc. 90(16):4480 (1968).

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