Coatings, coated articles and methods of manufacture thereof

Details Coatings, coated articles and methods of manufacture thereof Coatings, coated articles and methods of manufacture thereof

2007-01-02

2007-01-02

Azpuru, Carlos A. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S423000, C424S489000

Reexamination Certificate

active

10270092

ABSTRACT:
A multi-layer coating is particularly useful for the coating of implants such as orthopedic and dental implants, particularly metallic implants. The first layer comprises a bond coating of a dense material insoluble and inert in body fluids. The second layer comprises apatite and a binder. The first layer protects the metallic implants from corrosion, apatite dissolution, and interfacial reaction with apatite and the binder. The apatite in the second layer is a bioactive agent that can osteobond to tissue. The binder allows adjustment of the thermal expansion coefficient between the coating and the metallic substrate. This multi-layer coating has both high bond strength to implants and excellent bioactivity with the surrounding body tissue.

REFERENCES:
patent: 4675189 (1987-06-01), Kent et al.
patent: 5077132 (1991-12-01), Maruno et al.
patent: 5162430 (1992-11-01), Rhee et al.
patent: 5441536 (1995-08-01), Aoki et al.
patent: 5478237 (1995-12-01), Ishizawa
patent: 5730598 (1998-03-01), Story et al.
patent: 5763092 (1998-06-01), Lee et al.
patent: 6207218 (2001-03-01), Layrolle et al.
patent: 6280789 (2001-08-01), Rey et al.
patent: 6432437 (2002-08-01), Hubbard
patent: 2002/0076528 (2002-06-01), Tomsia et al.
patent: 40 20 598 (1991-01-01), None
patent: 40 32 570 (1992-04-01), None
patent: 0 447 744 (1991-01-01), None
Kurzweg, H., et al. “Development of plasma-sprayed bioceramic coatings with bond coats based on titania and zirconia”, Biomaterials, Elsevier Science Publishers BV., Barking, GB, vol. 19, No. 16, Aug. 1998, pp. 1507-1511, ISSN 0142-9612.
International Search Report, International Appln. No. PCT/US02/33029, International filing date Oct. 14, 2002; Date of mailing Sep. 10, 2003.
Gomez-Vega, J. M., et al.; “Glass-based coatings for titanium implant alloys”;J. Biomaterials Res., vol. 46, 549-559, 1999.
Han, Y. et al; “Characterization and stability of hydroxyapatite coatings prepared by an electrodeposition and alkaline-tretment process”;J. Biomed Mater. Res. vol. 54, No. 1, 96-101 (2000).
Sousa, S. R., et al.; “Effect of hydroxyapatite thickenss on metal ion relase from Ti6A14V substrates”; Biomaterials vol. 17, No. 4, 397-404 (1996).
Sun, L., et al.; “Material Fundamentals and Clinical Performance of Plasma-Sprayed Hydroxyapatite Coatings: A Review”; J. Biomed. Mat. Res. 58, 570-592 (2001).
Wei, M., et al.; “Electrophoretic Deposition of Hydroxyapatite Coatings on Metal Substrates: A Nanoparticulate Dual-Coating Approach”; Journal of Sol-Gel Science and Technology 21, 39-48, 2001.
Wei, M., et al.; “Interfacial bond strength of electrophoretically deposited hydroxyapatite coatings on metals”; Journal of Materials Science, Materials in Medicine 10; 401-409 (1999).
Yang, C. Y., et al.; “Bond degradation at the plasma-sprayed HA coating/Ti-B11-4V alloy intervace: anin vitrostudy”;Journal of Materials Science: Materials in Medicine 6, 258-265 (1995).
Zhitomirsky, I. et al.; “Electrophoretic deposition of hydroxyapatite”;Journal of Materials Science Materials in Medicine 8(4): 213-219, (1997).
J.M. Gomez-Vega et al., “Bioactive Glass-Mesoporous Silica Coatings on Ti6A14V Through Enameling and Triblock-copolymer-templated sol-gel Processing”, J. Biomedical Materials Research 56: 382-389; Mar. 2, 2001.
S.R. Sousa et al., Effect of Hydroxyapatite Thickness on Metal Ion Release from Ti6A14V Substrates, Biomaterials 1996, vol. 17, No. 4, pp. 397-404.

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