Coatings, coated articles and methods of manufacture thereof

Details Coatings, coated articles and methods of manufacture thereof Coatings, coated articles and methods of manufacture thereof

2008-01-22

2008-01-22

Kennedy, Sharon E. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

Reexamination Certificate

active

07320798

ABSTRACT:
A multi-layer coating is particularly useful for the coating of implants such as orthopedic and dental implants, particularly metallic implants. The first layer comprises a dense material insoluble and inert in body fluids. The second layer comprises apatite and a binder. The first layer protects the metallic implants from corrosion, apatite dissolution, and interfacial reaction with apatite and the binder. The binder allows adjustment of the thermal expansion coefficient between the coating and the metallic substrate. This multi-layer coating has both high bond strength to implants and excellent bioactivity with the surrounding body tissue.

REFERENCES:
patent: 4675189 (1987-06-01), Kent et al.
patent: 5037438 (1991-08-01), Davidson
patent: 5074916 (1991-12-01), Hench et al.
patent: 5077132 (1991-12-01), Maruno et al.
patent: 5162430 (1992-11-01), Rhee et al.
patent: 5441536 (1995-08-01), Aoki et al.
patent: 5478237 (1995-12-01), Ishizawa
patent: 5730598 (1998-03-01), Story et al.
patent: 5763092 (1998-06-01), Lee et al.
patent: 6013591 (2000-01-01), Ying et al.
patent: 6207218 (2001-03-01), Layrolle et al.
patent: 6280789 (2001-08-01), Rey et al.
patent: 6368993 (2002-04-01), Kim et al.
patent: 6432437 (2002-08-01), Hubbard
patent: 2002/0076528 (2002-06-01), Tomsia et al.
patent: 40 20 598 (1991-01-01), None
patent: 40 32 570 (1992-04-01), None
patent: 0 447 744 (1991-01-01), None
Gomez-Vega, J.M., et al.; “Glass-based coatings for titanium implant alloys”; J. Biomaterials Res., vol. 46, 549-559, 1999.
Han, Y. et al.; “Characterization and stability of hydroxyapatite coatings prepared by an electrodeposition and alkaline-treatment process”; J. Biomed Mater. Res. vol. 54, No. 1, 96-101 (2000).
Kurzweg, H., et al.; “Development of plasma-sprayed boiceramic coatings with bond coats based on titania and zirconia”, Biomaterials, Elsevier Science Publishers BV., Barking, GB, vol. 19, No. 16, Aug. 1998, pp. 1507-1511, ISSN 0142-9612.
International Search Report, International Application No. PCT/US02/33029, International Filing Date Oct. 14, 2002.
J.M. Gomez-Vega et al.; “Bioactive Glass-Mesoporous Silica Coatings on Ti6AL4V Through Enameling And Triblock-copolymer-templated sol-gel Processing”, J. Biomedical Materials Research 56; 382-389; Mar. 2, 2001.
S.R. Sousa et al.; “Effect of Hydroxyapatite Thickness on Metal Ion Release From Ti6Al4V Substrates”; Biomaterials 1996, vol. 17, No. 4, pp. 397-404.
Sun, L., et al.; “Material Fundamentals and Clinical Performance of Plasma-Sprayed Hydroxyapatite Coatings: A Review”; J. Biomed. Mat. Res. 58, 570-592 (2001).
Wei, M., et al.; “Electrophoretic Deposition of Hydroxyapatite Coatings on Metal Substrates: A Nanoparticulate Dual-Coating Approach”; Journal of Sol-Gel Science and Technology 21, 39-48, 2001.
Wei, M., et al.; “Interfacial Bond Strength of Electrophoretically Deposited Htdroxyapatite Coatings on Metals”; Journal of Materials Science: Materials in Medicine 10; 401-409 (1999).
Yang, C.Y., et al.; “Bond degradation at the plasma-sprayed HA coating/Ti-6Al-4V alloy interface: an invitro study”; Journal of Materials Science: Materials in Medicine 6, 258-265 (1995).
Zhitomirski, I. et al.; “Electrophoretic deposition of hydroxyapatite”; Journal of Materials Science: Materials in Medicine 8 (4): 213-219, (1997).

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