Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1991-09-19
1992-10-20
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424423, 424424, 424426, 424438, 424482, 424565, 530399, A61K 958, A61F 200
Patent
active
051568519
ABSTRACT:
Solid dosage forms of bioactive materials for parenteral administration such as porcine or bovine somatotropin pellets intended for subcutaneous implantation to improve food production of farm animals are coated with polyvinyl alcohol to extend the release characteristics of the material. The polyvinyl alcohol preferably has a molecular weight of from about 20,000 to 100,000, a degree of hydrolysis of at least about 98%, and is applied from an aqueous solution by spray coating to form a continuous uniform covering having a weight of from about 3 to 25 ug/mm.sup.2.
REFERENCES:
patent: 4855141 (1989-08-01), Eckenhoff et al.
patent: 4863736 (1989-09-01), Azain et al.
patent: 5091185 (1992-02-01), Castillo et al.
Castillo Ernesto J.
Eigenberg Kenneth E.
Patel Kanaiyalal R.
Sabacky Milton J.
Eberhardt Wayne R.
Monsanto Company
Page Thurman K.
Spear James M.
Tarter Stanley M.
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