Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2006-06-06
2006-06-06
Hartley, Michael (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S464000, C424S474000, C424S489000, C424S494000
Reexamination Certificate
active
07056534
ABSTRACT:
This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20–60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.
REFERENCES:
patent: 3873588 (1975-03-01), Osawa et al.
patent: 4235870 (1980-11-01), Leslie
patent: 4259315 (1981-03-01), Lippmann et al.
patent: 4259323 (1981-03-01), Ranucci
patent: 4340582 (1982-07-01), Kriesel et al.
patent: 4352791 (1982-10-01), Zaffaroni et al.
patent: 4519801 (1985-05-01), Edgren
patent: 4555399 (1985-11-01), Hsiao
patent: 4748023 (1988-05-01), Tamas et al.
patent: 4863743 (1989-09-01), Hsiao et al.
patent: 5035898 (1991-07-01), Chang et al.
patent: 5397574 (1995-03-01), Chen
patent: 5422122 (1995-06-01), Powell
patent: 5505962 (1996-04-01), Sparks
patent: 5651984 (1997-07-01), Powell
patent: 6245351 (2001-06-01), Nara et al.
Ethocel Polymers Dow Chemical Brochure, pp. 1-24, Feb. 1998.
Parikh, “Fluid-Bed Processing in the 1990s”, Atlantic Pharmaceutical Services, Inc., <www.apsoutsource.com/two.html.>, 7 pages.
Parikh, “Current Issues and Troubleshooting Fluid Bed Granulation”, Atlantic Pharmaceutical Services, Inc., <www.apsoutsource.com/three.html.>, 5 pages.
Sietz, et al., “Tablet Coating”, Chapter 12 fromThe Theory and Practice of Industrial Pharmacy,by Lachman et al., 3rdEdition, pp. 346-373.
Christenson Bradley L.
Dritsas Phillip W.
Faegre & Benson LLP
Hartley Michael
Upsher-Smith Laboratories, Inc.
Young Micah-Paul
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