Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure
Patent
1996-05-16
2000-08-01
Weiss, John G.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Stent structure
623 11, 623 12, 604 53, 604265, A61F 206
Patent
active
060960701
ABSTRACT:
A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one layer 18 of a bioactive material posited on one surface of structure 12; and at least one porous layer 20 posited over the bioactive material layer 18 posited on one surface of structure (12) and the bioactive-material-free surface. Preferably, the structure 12 is a coronary stent. The porous layer 20 is comprised of a polymer applied preferably by vapor or plasma deposition and provides a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, merely by condensation of a monomer vapor. Also disclosed is the method of manufacture of the device 10, as well as a method of using it in medical treatments.
REFERENCES:
patent: 4101984 (1978-07-01), MacGregor
patent: 4872867 (1989-10-01), Joh
patent: 5059166 (1991-10-01), Fischell et al.
patent: 5108424 (1992-04-01), Hoffman, Jr. et al.
patent: 5112457 (1992-05-01), Marchant
patent: 5197977 (1993-03-01), Hoffman, Jr. et al.
patent: 5282823 (1994-02-01), Schwartz et al.
patent: 5304121 (1994-04-01), Sahatjian
patent: 5314688 (1994-05-01), Kauffman et al.
patent: 5344444 (1994-09-01), Glastra
patent: 5348873 (1994-09-01), Matsuda et al.
patent: 5356433 (1994-10-01), Rowland et al.
patent: 5383927 (1995-01-01), De Goicoechea et al.
patent: 5383928 (1995-01-01), Scott et al.
patent: 5419760 (1995-05-01), Narciso, Jr.
patent: 5443458 (1995-08-01), Eury
patent: 5447724 (1995-09-01), Helmus et al.
patent: 5449382 (1995-09-01), Dayton
patent: 5455040 (1995-10-01), Marchant
patent: 5457113 (1995-10-01), Cullinan et al.
patent: 5464650 (1995-11-01), Bert et al.
Sushil Sheth, Vishva Dev, Harvey Jacobs, James S. Forrester, Frank Litvack, Neal L. Eigler, Prevention of Subacute Stent Thrombosis by Polymer-Polyethylene Oxide-Heparin Coating in the Rabbit Carotid Artery, Feb. 1995, JACC, 1001-29.
R.D. Falb, G.A. Grode, M.T. Takahashi and R.I. Leininger, Characteristics of Heparinized Surfaces, Oct. 11, 1968, Interaction of Liquids at Solid Substrates.
Photodynamic Therapy Application Approved, Feb. 15, 1996, Biomedical Technology Information Service.
Bruce Humphrey, Using Parylene for Medical Substrate Coating, Jan./Feb. 1996 Medical Plastics and Biomaterials.
Bates Brian L.
Fearnot Neal E.
Kozma Thomas G.
Ragheb Anthony O.
Voorhees, III William D.
Cook Inc.
Cuddihy Francis K.
Godlewski Richard J.
Med Institute Inc.
Weiss John G.
LandOfFree
Coated implantable medical device does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Coated implantable medical device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Coated implantable medical device will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-659548