Coated implantable medical device

Details Coated implantable medical device Coated implantable medical device

2007-12-27

2010-12-07

Prebilic, Paul (Department: 3774)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Drug delivery

C623S001150

Reexamination Certificate

active

07846202

ABSTRACT:
A coated implantable medical device10includes a structure12adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer16posited on one surface of the structure; and at least one layer18of a bioactive material posited on at least a portion of the coating layer16, where the coating layer16provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer20may be posited over the bioactive material layer18, where the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure12is a coronary stent. The porous layer20includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, and merely by condensation of a monomer vapor.

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