Coated composition and its preparation process

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424497, 424498, A61K 916

Patent

active

052905691

ABSTRACT:
A process for preparing a coated composition comprising a pharmaceutically active substance stable to heat, which comprises centrifugally granualting a mixture comprising said active substance and a first thermomelting material as a binder under heating without using any solvent and coating the resultant granules with a second thermomelting material as a coating material under heating, the melting point of the second thermomelting material being lower than that of the first thermomelting material.

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patent: 4450877 (1989-05-01), Walker et al.
patent: 4894234 (1990-01-01), Sharma et al.
patent: 4935246 (1990-06-01), Ahrens
patent: 4948589 (1990-08-01), Iijima et al.
patent: 4971804 (1990-11-01), Ghebre-Sellassie
patent: 5206219 (1993-04-01), Desai

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