Coated active agent-containing article

Details Coated active agent-containing article Coated active agent-containing article

1994-01-28

1995-03-28

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424459, 424462, 424463, 424474, 424482, 424490, 424497, 424479, 514770, 5147721, A61K 932, A61K 936, A61K 958, A61K 962

Patent

active

054015154

ABSTRACT:
Aqueous coating compositions for forming elastomeric films around active cores (e.g., drugs) comprising a dispersion of pre-crosslinked polyorganosiloxane latex particles, colloidal silica particles, and a water-dispersible organic material (e.g., polyethylene glycol) are disclosed and claimed. The elastomeric films formed by the coating compositions are used to control the rate of release of an active agent in the cores into an aqueous environment. Methods of formulating the coating compositions and active cores coated with the coating compositions are also disclosed.

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