Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1989-12-08
1993-05-04
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424501, 424502, A61K 916, A61K 918
Patent
active
052080382
ABSTRACT:
A composition which is includes discrete particles of a highly cross-linked macroporous hydrophobic polymer. The particles are of a first predetermined average diameter, and the polymer particles have entrapped therein and dispersed uniformly throughout an active ingredient. The composition also includes a coacervating agent mixed with the polymer particles in an amount sufficient to cause the polymer particles to collect forming dense clusters of coacervated particles of a second predetermined average diameter, the second predetermined average diameter being substantially in excess of the first predetermined average diameter.
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Colloid Science Krugt vol. II 1949 pp. 247-258.
Gressani Tina M.
Klein William L.
DeCesare Jim L.
Dow Corning Corporation
Kulkosky P.
Page Thurman K.
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