Chemistry: physical processes – Physical processes – Crystallization
Patent
1976-06-23
1977-04-26
Serwin, R.E.
Chemistry: physical processes
Physical processes
Crystallization
252408, G01N 3316
Patent
active
040198626
ABSTRACT:
Reagent compositions for use in CO.sub.2 analysis which comprise certain acids and/or buffered acids together with selected additives. The acids and buffered acids have pH less than 4 and a vapor pressure not in excess of 10mm mercury. Examples of these acids include lactic acid, citric acid, phosphoric acid, sulfuric acid, perchloric acid, malic acid, malonic acid, oxalic acid, naphthalenesulfonic acid, picric acid, sulfamic acid, and nitric acid. The additives, which can be used separately or with one another, are ethers of fatty alcohols and polyoxyethylene (having the structure R--O--(C.sub.2 H.sub.4 --O).sub.n H), glycerin, polyvinyl alcohol, and pH sensitive indicator dyes, including methyl red, p-nitrophenol, neutral red, phenolphthalein, and o-cresolphthalein. An improved method for analysis of CO.sub.2 in body fluids comprises the steps of adding these reagents to body fluid samples to release CO.sub.2 therefrom into a gas space, displacing the released CO.sub.2 to a detector, and measuring the amount of released CO.sub.2 in the detector. Generally, acid reagents including at least one of the ethers of fatty alcohols and polyoxyethylene are preferable for releasing CO.sub.2 from a body fluid sample.
REFERENCES:
patent: 3556950 (1971-01-01), Dahms
patent: 3639829 (1972-02-01), Harnoncourt
patent: 3681255 (1972-08-01), Wilfore
patent: 3874850 (1975-04-01), Sorensen et al.
patent: 3973912 (1976-08-01), Trafton
Corning Glass Works
Serwin R.E.
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