Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1993-10-20
1995-11-28
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530351, 530399, 530402, 424 852, C07K 14475
Patent
active
054709520
ABSTRACT:
Heterodimer proteins comprising a soluble .alpha. specificity determining cytokine receptor component and the extracellular domain of a .beta. receptor component function as CNTF and IL-6 antagonsists.
REFERENCES:
Baumann et al. (Apr. 24, 1993) J. Biol. Chem. 268:8414.
Davis et al. (Jun. 18, 1993) Science 260:1805.
Ip et al. (Jun. 26, 1992) Cell 69:1121.
Kishimoto et al. (Oct. 23, 1992) 258:593.
Murakami et al. (Jun. 18, 1993) Science 260:1808.
Stahl et al. (Apr. 15, 1993) J. Biol. Chem. 268:7628.
Stahl et al. (Aug. 27, 1993) Cell 74:587.
Devos et al. (1991) The EMBO J. 10:2133-2137.
Economides Aris N.
Stahl Neil
Yancopoulos George D.
Cermak Shelly Guest
Draper Garnette D.
Kempler Gail M.
Regeneron Pharmaceuticals Inc.
LandOfFree
CNTF and IL-6 antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with CNTF and IL-6 antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CNTF and IL-6 antagonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2014558