Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-04-15
1985-04-16
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 82, 546 83, 546120, 548362, A61K 3144, C07D47114, C07D491147
Patent
active
045115680
ABSTRACT:
Compounds of the formula (I): ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.7 and R.sup.8 are as described herein, D is oxygen or NR.sup.6, n is 1 or 2 and the physiologically acceptable salts thereof useful in reducing anxiety in an animal such as man. The compounds are potent anxiolytics having reduced side effects compared to known anxiolytics. Also pharmaceutical compositions, intermediates and methods of treatment and synthesis are described.
REFERENCES:
patent: 4051236 (1977-09-01), Harris et al.
Bare Thomas M.
Heald Anthony F.
ICI Americas Inc.
Kreek Louis F.
Schwartz Richard A.
Sheehan John M.
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