CNS assay for prediction of therapeutic efficacy for...

Details CNS assay for prediction of therapeutic efficacy for... CNS assay for prediction of therapeutic efficacy for...

2005-09-30

2010-12-28

Casler, Brian (Department: 3737)

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

C600S407000, C600S322000, C600S340000, C600S473000, C600S476000, C514S046000, C514S049000, C514S564000

Reexamination Certificate

active

07860552

ABSTRACT:
In general, the invention features methods for identifying therapeutic interventions for functional illnesses, e.g., neuropathic pain or depression, and methods for identifying markers for functional illnesses by employing an acute painful stimulus or other stimulus for a functional illness and measuring levels of CNS activity.

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Borsook et al., “CNS Response to a Thermal Stressor in Human Volunteers and Rats May Predict the Clinical Utility of Analgesics,”Drug Discovery Research68: 23-41 (2007).

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