CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzot

Details CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzot CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzot

1988-02-12

1989-07-11

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514337, 514397, 514443, 514444, 514469, 544333, 546269, 546274, 548336, 548491, 549 51, 549 60, 549467, 564387, A61K 3134, C07D30781

Patent

active

048472549

ABSTRACT:
The present invention relates to 3-aminomethyl derivatives of indane, dihydrobenzofurane, dihydrobenzothiophene, and indoline, acid addition salts thereof, isomers thereof, methods of preparation, pharmaceutical compositions and method of treating CNS-disorders such as schizophrenia, Parkinson's disease, depression, anxiety, migraine and senile dementia, or in the cure of cardiovascular diseases, by administering such a derivative.

REFERENCES:
patent: 3200132 (1965-08-01), Werner
patent: 3513239 (1970-05-01), Wiley et al.
patent: 4777168 (1988-10-01), Kuhla et al.
Hirose et al., Chemical Abstracts, vol. 81, 135855a (1974).

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