Cluster analysis of genetic microarray images

Details Cluster analysis of genetic microarray images Cluster analysis of genetic microarray images

2006-04-18

2006-04-18

Zeman, Mary K. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S020000, C435S006120, C707S793000, C382S129000, C382S130000

Reexamination Certificate

active

07031844

ABSTRACT:
A method for determining relative incidence of a binding substance within two biological samples is provided. The two samples are labeled with luminescent materials having different chromatic properties. An image of the luminescent materials upon a binding site of a microarray is analyzed as two clusters of data points scattered about respective representative pairs of chromatic intensity values. The relative incidence of the binding substance is determined as a ratio of differences between corresponding indices of the representative pairs.

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