Clot dissolving method

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Peroxide or compositions of or releasing gaseous oxygen or...

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514834, A61K 3340

Patent

active

058465677

ABSTRACT:
A method, composition and kit for effecting hemostasis of a bleeding point and/or dissociating an adherent blood clot at a lesion site on an internal organ, include a composition comprising hydrogen peroxide and surfactant. The composition is applied to the site thereby effecting hemostasis and clot dissociation and clearing the field for endoscopy.

REFERENCES:
patent: 3903265 (1975-09-01), Meisch
patent: 4198390 (1980-04-01), Rider
patent: 4477438 (1984-10-01), Willcockson et al.
patent: 5104644 (1992-04-01), Douglas
Hankin, et al., "Hydrogen Peroxide as a Topical Hemostatic Agent", Clinical Orthopaedics and Related Research, 1984 Jun.: (186):244-8.
Kalloo, et al., "Taking the Red Out of Bleeding Lesions: Improved Visualization and Clot Dissolution With Hydrogen Peroxide Spray", Gastrointestinal Endoscopy 1996 Apr.(43): Abstract 27 (Issue mailed Apr. 18, 1996).
The Merck Index, 12th Edition, Merck & Co., Inc., Whitehouse Station, NJ, 1996, entries 3264 and 4839.
USP Dictionary of USAN and International Drug Names, U.S. Pharmacopeia, Rockville, M.D., 1996, pp. 354 and 652.

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