Closure of bacterial ghost

Details Closure of bacterial ghost Closure of bacterial ghost

2005-10-04

2005-10-04

Smith, Lynette R. F. (Department: 1645)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Fusion of cells

C435S007320, C435S029000, C435S041000, C435S069700, C435S070100, C435S071200, C435S170000, C435S173100, C435S173800, C435S243000, C435S375000, C435S440000, C435S454000, C435S485000, C435S488000

Reexamination Certificate

active

06951756

ABSTRACT:
The invention relates to a method for preparing closed bacterial ghosts by means of vesicle membrane fusion and to the bacterial ghosts which can be obtained in this way. Active compounds, e.g. genetic material, cell components, pharmaceutical and agricultural active compounds and also markers or dyes can be packaged in the closed bacterial ghosts. Metabolic functions and, where appropriate, the ability of the cells to proliferate can be restored on packaging genetic material in the bacterial ghosts. The closed ghosts can be used in medicine, in the agricultural sphere and in biotechnology.

REFERENCES:
Hunter V et al.: “Bacterial ghosts as drug carrier and targeting vehicles.” Journal of Controlled Release, vol. 61, No. 1-2, Aug. 27, 1999, pp. 51-63, XP000907214; ISSN: 0168-3659; abstract; paragraphs '02.2!, '02.5!, '02.8!, '0004!.
Lubitz W et al.: “Extended recombinant bacterial ghost system.” Journal of Biotechnology, vol. 73, No. 2-3, Aug. 20, 1999, pp. 261-273, XP004180188; ISSN: 0168-1656; abstract; figure 3.

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