Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2006-06-09
2010-12-14
Griffin, Walter D (Department: 1797)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S305300
Reexamination Certificate
active
07851204
ABSTRACT:
A closure for a microreactor includes a cap that is configured to be inserted into a well of the microreactor. The cap, or at least a portion of the cap, is compliant so as to form a seal with the well when the cap is inserted. The cap includes an aperture that provides an airway between the inside of the well to the external environment when the cap is inserted into the well. A porous plug is inserted in the aperture, e.g., either directly or in tube that extends through the aperture. The porous plug permits gas within the well to pass through the aperture while preventing liquids from passing through to reduce evaporation and preventing microbes from passing through to provide a sterile environment. A one-way valve may also be used to help control the environment in the well.
REFERENCES:
patent: 3326401 (1967-06-01), De Long
patent: 5180073 (1993-01-01), Fay et al.
patent: 5989924 (1999-11-01), Root et al.
patent: 6106783 (2000-08-01), Gamble
patent: 6193088 (2001-02-01), Vincent et al.
patent: 6376233 (2002-04-01), Wolf et al.
patent: 6436351 (2002-08-01), Gubernator et al.
patent: 6500390 (2002-12-01), Boulton et al.
patent: 6602716 (2003-08-01), Klimant
patent: 6673532 (2004-01-01), Rao
patent: 2003/0235519 (2003-12-01), Sha et al.
patent: 2004/0077075 (2004-04-01), Jensen et al.
patent: 2005/0164373 (2005-07-01), Oldham et al.
patent: 2005/0176155 (2005-08-01), Klein et al.
patent: 0 976 453 (2000-02-01), None
patent: 1 069 181 (2001-01-01), None
patent: 1 122 181 (2001-08-01), None
patent: 1 580 261 (2005-09-01), None
patent: 02344 (1911-01-01), None
patent: 654 541 (1951-06-01), None
patent: WO 99/ 20394 (1999-04-01), None
patent: WO 02/26377 (2002-04-01), None
Liebsch et al “Luminescence Lifetime Imaging of Oxygen, pH, and Carbon Dioxide Distribution Using Optical Sensors” in Applied Spectroscopy vol. 54, No. 4, 2000 pp. 548-559.
M.M.Maharbiz, et al.,“Microbioreactor Arrays with Parametric Control for High-Throughput Experimentation” Biotechnology and Bioengineering, vol. 85, No. 4, Feb. 20, 2004, p. 376-381.
N. Szita, et al., “Monitoring of Cell Growth, Oxygen, and pH in Microfermentors” in Micro Total Analysis Systems (m-TAS) 2002, Y. Baba, S. Shoji, and A. van den Berg (Eds.). Kluwer, Dordrecht, The Netherlands, 2002, pp. 7-9, as downloaded from http://jensengroup.mit.edu
ew—students on Feb. 10, 2004.
Michel Martin Maharbiz, “Electrochemical Gas Generation for Cell Culture”, PhD Dissertation, University of California Berkeley, May 2003, pp. 1-170.
Michel M. Maharbiz et al., “A Microfabricated Electrochemical Oxygen Generator for High-Density Cell Culture Arrays”, Solid-State Sensor, Actuator and Microsystems Workshop, Hilton Head Island, SC, Jun. 2-6, 2002, pp. 259-264.
Shabbir B. Bambot, et al., “Potential applications of lifetime-based, phase-modulation fluorimetry in bioprocess and clinical monitoring”, Tibtech Mar. 1995 (vol. 13), pp. 106-115.
European Search Report mailed Oct. 11, 2007, for EP Application 07109914.7, which claims priority to U.S. Appl. No. 11/450,855.
Andronaco Gregory
Boyer Stephen G.
Klein David L.
Laidlaw Robert D.
Doe Shanta G
Griffin Walter D
Leydig , Voit & Mayer, Ltd.
Pall Microreactor Technologies, Inc.
LandOfFree
Closure for milliliter scale bioreactor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Closure for milliliter scale bioreactor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Closure for milliliter scale bioreactor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4215486