Clostripain catalyzed hydrolysis of preproinsulin analogs into c

Details Clostripain catalyzed hydrolysis of preproinsulin analogs into c Clostripain catalyzed hydrolysis of preproinsulin analogs into c

1994-08-08

1998-03-17

Weber, Jon P.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435220, 530303, C12P 2106, C12N 952, A61K 3828

Patent

active

057285438

ABSTRACT:
A process is described to specifically hydrolyze the amino acid chain of preproinsulin analogs to give the corresponding insulins. The hydrolysis is catalyzed by clostripain and, if necessary, carboxypeptidase B.

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