Clostridial toxin derivatives able to modify peripheral...

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated to proteinaceous toxin or fragment thereof

Reexamination Certificate

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C424S094670, C424S832000, C514S002600, C530S388220, C530S391700, C530S350000, C530S402000, C435S069100, C435S069700, C435S220000

Reexamination Certificate

active

06962703

ABSTRACT:
The invention relates to an agent specific for peripheral sensory afferents. The agent may inhibit the transmission of signals between a primary sensory afferent and a projection neutron by controlling the release of at least one neurotransmitter or neuromodulator from the primary sensory afferent. The agent may be used in or as a pharmaceutical for the treatment of pain, particularly chronic pain.

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