Closed-loop control of electrokinetic processes in...

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C204S451000

Reexamination Certificate

active

06905583

ABSTRACT:
A method for performing an electrophoretic separation on a microfluidic device includes applying an electric field to electrokinetically move a sample along a channel towards a location. The sample may be concentrated by application of the electric field. The method further comprises optically monitoring the location for at least a portion of the sample. Once the sample is detected, the electric field is automatically changed to further manipulate the sample. The sample may be spatially separated along a separation channel or channel portion. The closed-loop control of electric fields may be performed using a control unit adapted to apply a voltage potential between electrodes and an optical detector such as an LIF detector.

REFERENCES:
patent: 5378334 (1995-01-01), Dadoo et al.
patent: 5599432 (1997-02-01), Manz
patent: 6391622 (2002-05-01), Knapp
patent: 6685813 (2004-02-01), Williams
patent: 2002/0008029 (2002-01-01), Williams
patent: 2002/0079223 (2002-06-01), Williams et al.
patent: 2002/0189946 (2002-12-01), Wainright et al.
patent: 2004/0060821 (2004-04-01), Williams
patent: 1162455 (2001-12-01), None
patent: WO 92/13229 (1992-08-01), None
Bodor et al., “Isotachophoresis and isotachophoresis—zone electrophoresis separations of inorganic anions present in water samples on a planar chip with column-coupling separation channels and conductivity detection”, Journal of Chromatography A, 916 (2001) 155-165.
Burgi et al., “On-Line Sample Preconcentration for Capillary Electrophoresis”, Handbook of Capillary Electrophoresis, pp. 479-527, 1997.
Jacobson et al., “Microchip electrophoresis with sample stacking”, Electrophoresis, 1995, 16, pp. 481-486.
Kaniansky et al., “Capillary Electrophoresis Separation on a Planar Chip with the Column-Coupling Configuration of the Separation Channels”, Anal. Chem. 2000, 72, 3596-3604.
K{hacek over (r)}ivánková et al., “Isotachophoresis in zone electrophoresis”, Journal of Chromatography A, 838 (1999) pp. 55-70.
Stegehuis et al., “Analyte focusing in capillary electrophoresis using on-line isotachophoresis”, Journal of Chromatography, 591 (1992) pp. 341-349.
Wanders et al., “Isotachophoresis in Capillary Electrophoresis”, CRC Handbook of Capillary Electrophoresis: A Practical Approach, pp. 112-127, 1994.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Closed-loop control of electrokinetic processes in... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Closed-loop control of electrokinetic processes in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Closed-loop control of electrokinetic processes in... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3500979

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.