Cloprostenol and fluprostenol analogues and their use to treat g

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514546, 514548, 514573, 514684, 514712, 514717, 514719, 560 53, 560 60, 560255, 562452, 568330, 568631, A61K 31557, C07C 5946, C07C 69608

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active

056657730

ABSTRACT:
Disclosed is the use of cloprostenol and fluprostenol analogues for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.

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Stjernschantz et al., "Phenyl substituted prostaglandin analogs for glaucoma treatment," Drugs of the Future, 17(8):691-704 (1992).
Zajaez et al., "Effect on Human Eye of Prostaglandin and a Prostaglandin Analogue Used to Induce Abortion," IRCS Medical Science: Clinical Medicine: Clinical Pharmacology & Therapeutics: Drug Metabolism & Toxicology: The Eye: Reproduction, Obstetrics & Gynecology, 4:316 (1976).
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