Multicellular living organisms and unmodified parts thereof and – Method of making a transgenic nonhuman animal – Via microinjection of a nucleus into an embryo – egg cell – or...
Reexamination Certificate
2007-11-06
2007-11-06
Crouch, Deborah (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Method of making a transgenic nonhuman animal
Via microinjection of a nucleus into an embryo, egg cell, or...
C800S008000, C800S017000, C800S281000, C800S323200, C800S319000
Reexamination Certificate
active
09394902
ABSTRACT:
An improved method of nuclear transfer involving the transplantation of donor differentiated pig cell nuclei into enucleated pig oocytes is provided. The resultant nuclear transfer units are useful for multiplication of genotypes and transgenic genotypes by the production of fetuses and offspring. Production of genetically engineered or transgenic pig embryos, fetuses and offspring is facilitated by the present method since the differentiated cell source of the donor nuclei can be genetically modified and clonally propagated.
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Cibelli Jose
Golueke Paul
Robl James
Stice Steven L.
Crouch Deborah
Finnegan Henderson Farabow Garrett & Dunner LLP
University of Massachusetts, a Public Institution of Higher Educ
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