Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-12-16
2000-06-13
Hauda, Karen M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 4353201, 435325, 435363, 435366, 536 231, 536 235, C12N 1563, C12N 1509, C12N 510, C12N 1500
Patent
active
060748427
ABSTRACT:
The present invention provides isolated nucleic acid sequences, i.e., polynucleotides, which encode a family of perilipin proteins. The present invention also provides isolated, substantially purified perilipin proteins which are useful as markers for differentiating true adipocytes from non-adipocyte cells which, as a result of pathophysiological conditions, assume adipocyte characteristics and become lipid-laden. The present invention further provides methods for producing a substantially purified perilipin protein and methods for detecting the presence of such perilipin proteins in a biological samples.
REFERENCES:
patent: 4675285 (1987-06-01), Clark et al.
patent: 5585462 (1996-12-01), Londos et al.
Kimmel et al. (Jan. 18-25, 1991) J. Cell. Biochem. Suppl 15B, p. 31, abstract CA309.
Greenberg et al. (May 1991) Clinical Research abstract.
Maruyama et al. (1986) Nuc. Acids Res 14: r151-r197.
Webster's II New Riverside University Dictionary, Soukhanov et al. (eds.) 1984, Houghton Mifflin Company, Boston, MA, p. 67.
Egan John J.
Greenberg Andrew S.
Kimmel Alan R.
Londos Constantine
Hauda Karen M.
The United States of America as represented by the Department of
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