Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof
Patent
1995-06-07
2000-06-20
Scheiner, Laurie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Allergen or component thereof
4241841, 4241851, 4242001, 435 74, 435 691, 435 693, 4352523, 436826, 530350, 530324, 530325, 530326, 530327, 530328, 530329, A61K 3935
Patent
active
060775181
ABSTRACT:
Isolated allergens of Dermatophagoides (house dust mites) particularly of the species and Dermatophagoides pteronyssinus, which are protein allergens or peptides which include at least one epitope of the protein allergen. In addition, the or peptides encoded by the isolated DNA, their use as diagnostic and therapeutic reagents and methods of diagnosing and treating sensitivity to house dust mite allergens.
REFERENCES:
Stewart et al. (1986) Asian Pacific J. of allergy & Immun, 4(1):71, 1986.
Abstracts from the Annual Meeting (1986) "The physiochemical characterization of a mojor protein allergen from the house dust mite, Dermatophagoides" Asian Pacific J. of Allergy & Immunol. 4(1):71 (abstract);.
Chapman et al. "II. MITE ALLERGENS 1. Epitope mapping of mojor dust mite (deratophagoides) allergens using monoclonal antibodies" The UCB Institute of Allergy, MITE ALLERGY A World Wide Problem, Bad Kreuznach, Sep. 1-2, 1987.
Chemical Abstracts vol. 108, p. 148, abstract No. 217095, Chua et al. "Sequence analysis of cDNA coding for a mojor proteases" (1988) abstract.
Chemical Abstracts vol. 105, (1986 p. 552, (abstract No. 189004) Yasaueda, Hiroshi et al. "Isolation and characterization of two allergens from Dermatophagoides farnae".
Heymann, et al. (1986) "Antigen Der f l from the dust mite Dermatophagoides farinae: structural comparison with Der p l from Dermatophagoides pteronyssinus andepitope specificity of murine lgG and human igE antobodies" Journal of Immunology 137:2841-2847;.
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Simpson Richard John
Stewart Geoffrey Alexander
Thomas Wayne Robert
Turner Keven
Immulogic Pharmaceutical Corporation
Mandragouras, Esq. Amy E.
Remillard, Esquire Jane E.
Scheiner Laurie
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